Spain's David Ferrer routed Kazakhstan's Mikhail Kukushkin 6-2, 6-3 to advance to the second round of the Abierto Mexicano Telcel in this Pacific resort city.

Ferrer, a three-time champion of this event when it was played on clay, was equally comfortable on the tournament's new hard-court surface on Tuesday evening, needing just an hour and a half to dispatch his 57th-ranked opponent.

The 31-year-old world No. 4 saved the only two break points he faced while consistently threatening Kukushkin on his service games. Ferrer struggled to capitalize on his break points and converted just three of his 16 opportunities, but that was more than enough for the comfortable win.

The victory was Ferrer's 250th of his career on a hard court and it set up a second-round battle against countryman Feliciano Lopez, who defeated Edouard Roger-Vasselin 6-4, 6-2 on Tuesday.

"Feliciano is a player who really makes me uncomfortable, so I'll have to play very well. I have to be focused and organized with my game," the top seed, who lost last year's final to countryman and current world No. 1 Rafael Nadal, said.

Ferrer narrowly leads his head-to-head against the 37th-ranked Lopez 7-6.

"David has played in Mexico for many years. He's won the tournament three times. We've had great matches, great battles and I hope this'll be another one," Lopez said.

Ferrer is playing his third tournament in three weeks (winning the event in Buenos Aires before losing in the semis of Rio de Janeiro last week), and he said he arrived in Acapulco tired and having had little recovery time.

"I've had two hard weeks, a long trip, and now I need to rest and recover well for the match against Feli," the world No. 4 said.

In other matches Tuesday involving top seeds, second-seeded Scotsman Andy Murray rallied to defeat Spain's Pablo Andujar 3-6, 6-1, 6-2, but third-seeded American John Isner was upset by fellow big server Ivo Karlovic of Croatia 7-6 (7-4), 7-6 (7-5). EFE