Marco Antonio scored with a header off a corner in the first half to lead Gremio to a 1-0 win over Millonarios of Colombia in the quarterfinals of the Copa Sudamericana on Tuesday.

The Brazilian club can reach the semifinals of the South American competition with a draw in the second leg on Nov. 15 in Colombia.

Gremio, coached by Vanderlei Luxemburgo, controlled possession from the start and had most of the scoring chances at the Olimpico Stadium.

Marco Antonio easily scored from close range off a corner taken by World Cup veteran playmaker Ze Roberto in the 37th minute.

Gremio midfielder Leo Gago struck the post with a low shot in the 76th and striker Andre Lima had a goal disallowed because of offside in the 90th.