Atletico Madrid had its first home league defeat of the season after going down 2-0 to 10-man Real Betis on Sunday to increase the pressure on coach Gregorio Manzano.

Alex Pozuelo scored in the 54th minute and substitute Roque Santa Cruz added a second in stoppage time to give Betis a second straight victory and boost its own beleaguered coach, Pepe Mel. Pozuelo was sent off in the 72nd.

Atletico is without an away win in seven Spanish league matches but its impressive home form had given Manzano some protection.