Beckham's 12-year marriage to former Spice Girl wife Victoria has already produced four kids -- Brooklyn, 12, Romeo, nine, Cruz, six, and the couple's only daughter, Harper Seven, who was born in July.
"If we were lucky enough to have another one, it would be great," the former England captain, 36, said during Friday's taping of "The Ellen DeGeneres Show."
"We always spoke about having a big family. We love children. We are very blessed to have four healthy children so if one comes along that would be amazing," he said, according to excerpts obtained by People magazine.
Beckham has spoken previously of his desire to ultimately have five children.
Just two months after the birth of her fourth child, Victoria, 37, was flaunting her flawless figure in New York for Fashion Week with baby Harper in tow.
She showed her Spring/Summer 2012 Ready to Wear Collection on September 11 at the New York Public Library's Astor Hall.