Argentina's Velez Sarsfield was held to a goalless draw by domestic rivals Argentinos Juniors in the first leg of their Copa Sudamericana second-round clash.

Clearly missing the departed Santiago Silva up front following his move to Fiorentina in Italy, Velez dominated but failed to get the breakthrough.

Juan Manuel Martinez created plenty of chances but Guillermo Franco and Augusto Fernandez proved wasteful up front.

In Venezuela, Peruvians Universitario secured a valuable 2-1 win away to Anzoategui.

Debutant Alvaro Ampuero opened the scoring in the 29th minute with a shot from the edge of the box after Anzoategui had a spell of dominance.

Four minutes after the break, Andy Polo lead a fast counter-attack and crossed for Johan Fano, who doubled the advantage with a header.

Armando Maita reduced the gap but Anzoategui could not avoid the home defeat.