Arsene Wenger admitted he had been left embarrassed by the size of their 8-2 defeat against Manchester United but denied he would quit his post despite the mounting pressure.
During an avalanche of goals, Wayne Rooney surpassed 150 United goals as Ashley Young (two), Danny Welbeck, Nani and Park Ji-sing all got their names on the scoresheet.
An under-strength Arsenal replied through Theo Walcott and Robin van Persie, but Wenger's biggest Premier League defeat was soured further by the sending off of Carl Jenkinson.
"You feel humiliated when you concede eight goals," he told Sky Sports 1.
"It was a terrible day for us, it was a combination of an under-strength team and weakness.
"We collapsed physically in the second half."
Asked if he might think about resigning during the upcoming international break, he was initially coy, saying: "I believe we have a break before the next game."
He then ruled out the possibility, adding: "No, not at all."
With three days to go before the end of the transfer window Wenger is under pressure to bring in new names, although he was again guarded about the addition of any players.
"I know that in England when you lose a game signings are always the solution," he added.
"We had eight players out today. Anybody would suffer with eight players missing."
United manager Sir Alex Ferguson was surprised by the ease of his side's success despite Arsenal missing so many first-team regulars.
"It is (a surprise) because when you play Arsenal you expect a difficult game," he said.
"If you look at Arsenal the team is weakened - but we still did the job.
"We got careless at times and they made chances because they still have quality up front
"But overall we are very satisfied that we kept the performance levels up."
With his counterpart Wenger likely to come in for more criticism this week, Ferguson again leapt to the Frenchman's defence.
"I think it is unfair to criticise him," he said.
"The job he's done for Arsenal and the philosophy he has - he has given Arsenal some very entertaining players.
"He's also sold well and looked after the Arsenal coffers. People forget these things. It's a cynical world now and when you lose a few games the judges come out."
Rooney said: "The performance today was incredible and we deserved the result.
"Whether or not Arsenal have a full-strength squad every time we play them we have a go and try score.
"They had some players out but that should take nothing away from us."
Rooney's landmark goal also continued a trend against the Gunners.
"A lot of my milestone goals have come against Arsenal," he added.
"My first goal when I was at Everton was against them and my first United goal in the Premier League came against them too."
Also speaking after the game, former Arsenal midfielder Paul Merson suggested the departure of David Dein had been the catalyst for Arsenal's slump.
The club's former vice-chairman, Dein was a close ally of Wenger's and assisted him in recruiting a number of big-name signings prior to his departure in 2007.
"They miss David Dein," Merson said. "Since he went out, it's gone down.
"He was someone to do the signings, someone to talk to. David Dein was part of it when they signed the (Marc) Overmars, (Emmanuel) Petit, (Patrick) Vieira and (Thierry) Henry.
"Since David Dein went, the players haven't been like that. Arsenal is a saga, haggling over money for players, making it (deals) last three days.
"Sir Alex Ferguson will be sitting on a beach next week. Wenger will be in his office trying to sign a player."
Merson also stood by rookie defender Jenkinson, who suffered a nightmare day.
"One minute he was playing non-league football, today he's playing at Old Trafford...," he added.
"The poor lad got sent off, he didn't deserve it."
The former England midfielder did give his backing to Wenger, though, and encouraged him to make strides in the transfer market before the window closes on Wednesday.
"I would never get rid of Arsene Wenger," he said.
"They (the fans) have got to remember that if you get what you wish for it doesn't always work.
"They have got to buy one or two centre-halves, a central midfielder and a centre forward. You win stuff through the middle."