The Gunners manager continues to have to fend off speculation regarding the future of his club captain.
Reports suggesting Fabregas will soon return to his Catalan roots at Barcelona refuse to go away, with the saga having dragged on for some years now.
The Spain international has announced in the past that he would welcome the opportunity to head home, helping to fan the flames.
His words have often incited a response from those already at Camp Nou, with the likes of Xavi having been increasingly vocal in their support of a deal.
The World Cup winner was at it again on Wednesday when speaking to Barcelona's official website.
He said: "I spoke to Cesc in Ibiza and he said he was suffering because he wanted to come.
"It's more like, he did everything he could to come and wants to leave Arsenal - although he made it clear that now everything depends on the selling club."
Wenger is disappointed with Xavi for discussing an issue which has nothing to do with him and admits he is growing tired at having to cover old ground.
The Gunners boss said: "What is important is that Cesc Fabregas is contracted to Arsenal. That is a fact. Arsenal wants to keep him and all the rest is comment.
"If I found Barcelona in exactly the same position, I believe a mutual respect between the clubs should stop this kind of comment.
"If it is true then it is very disrespectful and it is not the first time that Xavi has been disrespectful to Arsenal."
Fabregas, 24, is a product of the Barcelona youth system but joined Arsenal in 2003 and has since become a key figure at the club.
Barca coach Pep Guardiola earlier revealed he hoped there will be progress in the pursuit of Cesc Fabregas before the end of the week.
Guardiola is reported to be unhappy with Barcelona president Sandro Rosell for his failure to sign Fabregas earlier in the summer, but is certainly hoping for an imminent update on the situation.
"Now the situation about moves for reinforcements is very complicated, but I'm hopeful in the next few days it will become clear," he said on Catalunya Radio.
"I'm always optimistic."