The former governor of Tabasco state gave federal prosecutors a statement as part of the investigation into allegations that he misused public funds while in office, the Mexican Attorney General's Office said.
Andres Granier and his attorney, Eduardo Luengo Creel, appeared at the public corruption unit in Mexico City on Wednesday, the AG's office said.
Granier was advised of the case against him "as a result of the complaint filed by the government of the state of Tabasco," the AG's office said.
"Afterward, Mr. Granier Melo requested that he be allowed to give a statement to federal prosecutors," the AG's office said.
Tabasco Gov. Arturo Nuñez said on Feb. 22 that an audit of the Granier administration found 1.91 billion pesos ($152 million) was missing.
Granier said in a television interview Monday in the United States that he did not break the law and planned to return to Mexico to clear his name in the courts.
"I want to repeat and make it very clear that I am innocent and I am going to show it," Granier said on Televisa's Primero Noticias show.
The politician, who stands accused of illicit enrichment, had been living in the United States for the past few months due to health problems.
The former governor told Televisa he was in the United States for health reasons and not to avoid Mexican prosecutors, who ordered him to answer questions on May 30 about alleged misuse of public funds during his 2007-2012 term.
Granier, however, failed to show up for the meeting with investigators.
The former governor denied in a statement released by his defense attorneys that he committed any crimes.
"I did not instigate, formulate, carry out or cover up any actions or omissions that caused harm to the public coffers of Tabasco state or unduly enriched me," Granier, a member of the ruling Institutional Revolutionary Party, or PRI, said.
The former governor denied that he was involved in any "financial or business schemes carried out to harm the public patrimony of said federal entity."
Granier alleged that Nuñez, a member of the leftist Party of the Democratic Revolution, or PRD, was behind a campaign to discredit the PRI.
The former governor arrived in Mexico on Tuesday, telling reporters he returned to the country to clear his name. EFE