Firefighters have extinguished the flames at one of the three tanks still burning at Venezuela's Amuay refinery, where more than 40 people died in an explosion over the weekend, President Hugo Chavez said.

"The latest: at this time, the fire at tank 200 in Amuay has been extinguished!" Chavez said in a Twitter posting.

The Amuay refinery is one of three that make up the Paraguana Refinery Complex, or CRP, the largest in this South American country and one of the largest in the world.

Saturday's explosion set two fuel tanks on fire, with the flames later spreading to a third tank.

The work of putting out the fire in tank 203 is "advancing at 75%! And we are with our heroic PDVSA firefighters in the struggle!" the president said.

"Now we will focus on tank 204, to completely extinguish the fire! With the help of God, we will get it done!" Chavez said, referring to the third tank that caught fire.

Tank 204 caught fire on Monday after the heat spread from the nearby tanks, sparking the blaze.

The fire is out in tank 200 and firefighters are making progress in putting out the other blazes, Oil and Mining Minister Rafael Ramirez told state television.

More than 200 firefighters are working to put out the blazes, Ramirez said.

At least 41 people were killed, six people were reported missing and more than 80 others were injured in the blast, with 31 people still hospitalized in Punto Fijo, where the refinery is located, and Maracaibo, officials said. EFE