More than 40 people died in a wave of violence over the weekend in Mexico, officials said.

The Pacific resort city of Acapulco was one of the worst-hit areas, registering at least 12 murders.

Ten men and two women were gunned down Saturday night in different neighborhoods in Acapulco, which is in Guerrero state, city officials said.

A couple was gunned down and four men were murdered in separate incidents, with investigators having no motive for the killings.

Three unidentified bodies were found Saturday night inside a taxi, while a shootout at a taco stand left two men and a woman dead on Sunday morning.

Acapulco, one of Mexico's most famous tourist destinations, has been plagued by drug-related violence in recent years.

State and federal officials responded to the violence by launching a security operation in Acapulco's tourist districts, allowing municipal police officers to focus on peripheral areas.

Guerrero Gov. Angel Aguirre Rivero launched a security operation last year with the support of the federal government to step up security in areas frequented by foreign and domestic tourists.

"Operation Safe Guerrero" was launched on Oct. 6, 2011, in an effort to reduce the soaring crime rate in the state.

Acapulco, a favorite among Mexican and foreign tourists for decades, has lost business to other destinations due to the violence.

In the northern state of Coahuila, meanwhile, six people were murdered in the city of Torreon, the state Attorney General's Office said.

Four people were gunned down, with one killed inside a house, two outside the same house and another found dead in a nearby street.

The body of a woman who had been shot in the neck was found inside a house in Torreon, while the battered body of a man was discovered in a cemetery.

Torreon is in the La Laguna region, which includes parts of Coahuila and neighboring Durango state.

The region is at the center of a brutal turf war between the Los Zetas and Sinaloa drug cartels, with the Zetas controlling Coahuila's largest cities, including Saltillo, the state capital, Torreon and Piedras Negras.

In Morelos, a state in central Mexico, the bullet-riddled bodies of two men were found inside a vehicle, state prosecutors said.

Northern Mexico was not spared from the violence, with a man and a woman gunned down in Monterrey, the capital of Nuevo Leon state, on Saturday afternoon, the State Investigations Agency, or AEI, said.

The Los Zetas cartel has been battling the Gulf cartel for control of the Monterrey metropolitan area and smuggling routes into the United States.

These 22 killings come on top of another 22 murders reported earlier in the weekend, bringing the death toll so far to at least 44 people.

More than 50,000 people, according to official figures, have died in drug-related violence in Mexico since late 2006.

The Movement for Peace with Justice and Dignity, which was founded by human rights activist and poet Javier Sicilia, puts the death toll from Mexico's drug war at 70,000. EFE